Three children and a woman were airlifted to hospital on Saturday night following a head-on collision between two cars on the Princes Highway at Traralgon.
Latrobe Highway Patrol said a Ford sedan travelling west collided with a Holden Colorado travelling east just after 6pm.
The driver of the Ford, a 32-year-old woman, was airlifted to hospital with serious injuries.
The driver of the Holden, a 29-year-old woman, was transported by road to hospital in a serious condition.
Her three passengers, all aged under 10, were seriously injured and airlifted to The Royal Children's Hospital.
Anyone with dash camera footage or who witnessed the incident, which happened five kilometres east of Wilmot Court, is urged to phone Crime Stoppers on 1800 333 000 or visit crimestoppersvic.com.au.
Family history records
A folder containing detailed family history records has been handed into Moe police.
Anyone with information is asked to phone Moe Police Station on 5128 1100.
A credit card stolen from a car parked in Yarragon address was used on a personal shopping spree, police say.
Trafalgar police said the thieves broke into a number of cars in the area between May 9 and 10. Anyone with information is asked to phone Trafalgar Police Station on 5633 1188 or Crime Stoppers on 1800 333 000.